Verrutop – Topical Treatment for Verruca

What is a Verruca?

Verruca is a skin infection caused by The Human Papilloma Virus. Viruses are made up of complex proteins and invade the outermost layer of the skin (epidermis). It usually appears as a plaque of hard skin with an irregular border and can have black dots (blood vessels) scattered throughout. Verruca can be very painful and can appear on any part of the body.

It is important to remember that the virus is contagious and can be spread to others 

What is Verrutop?

Verrutop is a new treatment in the UK and is a Class 2A Healthcare Product, which should only be used by a qualified medical professional.

It is a topical solution based on a unique combination of three organic acids, lactic, acetic, and oxalic, which are combined with copper and zinc salts plus nitric acid to produce “Nitric Zinc Complex”.

How does it work?

Verrutop in a unique combination of three organic acids, namely lactic, acetic and oxalic which are combined with copper and zinc salts (accelerants) plus nitric acid to produce “Nitic Zinc Complex”. This Complex triggers and accelerates two keys processes, Desiccation and Denaturation. Verrutop is not a caustic agent, instead its combination acts together to produce nitrites, which denature viral proteins and desiccate the verruca, leaving intact epithelium behind as if the verruca had not been there.

Desiccation is a process of dehydration. HPV virus is a protein enclosed in a capsid which is a protein-based covering. The virus itself consists of a double stranded Deoxyribonucleic acid (DNA) which is inserted into host cells, such as skin, where it can replicate. DNA is the genetic material which allows the virus to replicate. The capsid and DNA are highly sensitive to the effects of desiccation which leads to their breakdown and destruction and thus prevents viral replication.

Denaturation is a process, which breaks down and weakens the structure of DNA, which is found in the viral proteins. This important molecule is critical to the survival of the virus. DNA contains all the genetic material that allows the virus to replicate and drive reproduction, growth and development. Denaturation causes a disruption of this activity and leads to viral cell death.

How effective is Verrutop treatment?

A study involving 200 patients with 766 verrucae demonstrated an 89.3% clearance rate within 6 treatment sessions.

What can I expect if I have Verrutop treatment?

Patients will always be booked in for an Initial Assessment. During this appointment the Specialist Podiatrist will assess if you are suitable for Verrutop.

Verrutop is applied to verruca via a small capillary tube. The surface of the verruca is covered in the solution. The verruca may change colour and appear a white/yellow colour. Patients will be advised to apply surgical spirit to the verruca twice a day between treatments to aid the desiccation process. The process will be repeated every two weeks up to a maximum of six sessions.

Is the treatment painful?

The treatment in the vast majority of cases is painless. Some patients may experience a slight tingling or burning sensation. If this is the case, it is short term.

Is everyone suitable for treatment?

Verrutop is a safe topical treatment.

Verrutop should not be used:

  • On healthy skin
  • On tumours, keloids or flat warts
  • On children under the age of 6 years
  • On women who are pregnant or breast feeding
  • On patients with impaired circulation or sensation
  • On patients already using other topical treatments
  • On patients already undergoing other skin treatments, e.g. skin cancer


If you would like to book an Assessment at The Hartland Podiatry Clinic please contact the clinic either by telephone on 01235 798313 or complete the form below and a member of staff will contact you to book your Assessment.

01235 798313

Monday:        9.00am – 5.00pm
Tuesday:        9.00am – 5.00pm
Wednesday:  9.00am – 5.00pm
Thursday:      9.00am – 5.00pm
Friday:            9.00am – 5.00pm
Saturday:       Closed
Sunday:          Closed